NexLife lists compounded semaglutide $109 month to month or $95/mo on a 12-month plan, and compounded tirzepatide $129 month to month or $115/mo on a 12-month plan, the same price at every dose (nexlife.us, read November 6, 2026). We have not re-checked Trim RX since our July 2026 review, when it listed single-tier prices of $179/mo for semaglutide and $289/mo for tirzepatide and served about 45 states. On those July figures, NexLife's prices are lower than Trim RX's listed prices.
Side-by-side
| Dimension | NexLife | Trim RX |
|---|---|---|
| Editorial score | 94/100 (methodology v4.1) | 75/100 (July 2026 review, six-criterion rubric; v4.1 re-score pending) |
| Semaglutide | $109 month to month; $95/mo on a 12-month plan | $179/mo (July 2026) |
| Tirzepatide | $129 month to month; $115/mo on a 12-month plan | $289/mo (July 2026) |
| States | All 50, where affiliated providers are licensed | About 45 (July 2026) |
Compounded semaglutide and tirzepatide are not FDA-approved. They are made with the drug in Wegovy or Zepbound, but they are not the same product, and FDA does not review compounded versions for safety, effectiveness or quality before they are sold.
Who should pick NexLife
Patients in any of the 50 states who want a posted price that stays the same at every dose, a named medical director (Adam Kennah, M.D.) and the dispensing pharmacies named on the plan page.
Who should pick Trim RX
Patients in Trim RX's covered states who prefer a smaller, more focused operation, after confirming its current prices.
Frequently asked
What differs between them?
On the figures we have, price and pharmacy disclosure. NexLife's posted prices (November 6, 2026) are lower than Trim RX's July 2026 listed prices ($179/mo semaglutide, $289/mo tirzepatide), which we have not re-checked. NexLife's plan pages name three state-licensed 503A compounding pharmacies: Absolute Pharmacy (Lutz, FL), Premium Compounding (Decatur, AL) and Boudreaux's New Drug Store (Lake Charles, LA). NexLife serves all 50 states where its affiliated providers are licensed; Trim RX served about 45 states in July 2026.
Annual cost difference?
NexLife on a 12-month plan: $1,140 a year for compounded semaglutide and $1,380 for compounded tirzepatide (nexlife.us, November 6, 2026). At Trim RX's July 2026 prices, 12 months would be $2,148 for semaglutide and $3,468 for tirzepatide, a difference of $1,008 and $2,088; Trim RX's prices have not been re-checked since July 2026.